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Deep Brain Stimulation

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The patient is a male of Parkinson disease that started 7 years ago with gradual disease progression.

Professor's Name: Dr Assistant Proff. Ahmad Soltani

Subject: Deep Brain Stimulation

Department:  Neurosurgery Shiraz Uniuversity of Medical Sciences

Hospital: Namazi Hospital

Patient's History: The patient is a male of Parkinson disease that started 7 years ago with gradual disease progression.

The patient is a male of Parkinson disease that started 7 years ago with gradual disease progression.

In spite of adjustment of his medication by expert neurologist working in the field of movement disorder. He suffered from frequent off stat that he could not even self care himself.

By increase a dose of medication he developed sever dyskinesia.

The patient candidate for implantation of DBS in subthalomic nucleus bilateraly.
After the surgery his symptom improved so much that now he is able  to live and work independently and even he drive a car and his quality of life improved satisfactory.

DBS Surgery:
DBS means deep brain stimulation. It is a stereotactic procedure for implanting fine electrod in deep area of brain in a specific nucleus, to deliver a high frequency
stimulation to the target nucleus
It has several indication including:
1-    Movement disorder like Parkinson’s disease and essential tremor
2-    Dystonia
3-    Psychiatric disorder like obsessive compulsive disorder and major depression
4-    Epilepsy

The mechanism of action is not to completely known and several mechanism are involved. But the final common pathway is via making a noise in the abnormal neuronal network, so reduce the disease severity. In the case of Parkinson disease the abnormal network of cortico-basal gangalio-thalmo-cortical loop after implantation of DBS works more normally so leads to improvement of clinical symptom and also reduction of the dose L-dopa and subsequently decreased dyskinesia.

Image

Befor Surgery

 

 

After Surgery

 

 

Download Video:

befor surgery

after surgery: after surgery 1       after surgery2

Last modified on Wednesday, 05 July 2017 08:35

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